This case has been wending its way through the courts for awhile, but Akamai (NSDQ: AKAM) has won the latest round in its longstanding patent infringement case against rival CDN Limelight (NSDQ: LLNW). In a statement, the company said that a Boston jury found that Limelight had infringed on four of its patents, and it said the company would have to pay a $45 million penalty. Akamai says it will ask the court to issue a permanent injunction on Limelight’s use of the patents. Limelight, which has had nothing go right for it since coming public last year, is off over 35 percent on the news and is now down over 80 percent from its 52-week highs. Akamai is currently up over 7 percent. Release.

This may not be the end of the story, of course. A Limelight spokesman says the company will appeal, reports Reuters.

Update 1: Limelight waited until 5:34 PM (ET) on a Friday to offer its official response to the verdict: “We are disappointed with the jury’s verdict in this matter. We strongly believe that, like other companies that follow long-established Internet standards, we do not infringe the patent in this case. We will continue to remain a competitive choice in the marketplace as we pursue all appropriate legal avenues.”

Update 2: The jury verdict document is embedded below (RSS readers will have to click). You can also download the 9 page verdict from here.

• Limelight Wins Prelim Ruling Against Akamai on Patent Lawsuit